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Oral leukoplakia: signs of the disease and methods of getting rid of it

how dangerous oral leukoplakia

The appearance of keratinized areas of multilayered epithelium on the mucous membranes suggests leukokeratosis. It develops in the mouth, genital, and in some cases, it is formed in the internal organs: vagina, uterus, bladder, esophagus, etc.

The course of the disease almost does not cause discomfort and in a stable form can accompany human life. The danger is a possible transformation into a malignant form of leukokeratosis.


Multifactorial etiology of oral leukoplakia allows speaking not so much about the causes of disease, as much of the circumstances which cause it. The leading role has external factors.

The chemical, thermal or mechanical stimuli, which create conditions for the replacement of mucosal by keratinized epithelium include:

  • smoking, which is in both chemical and thermal action;
  • spices, spicy and sour dishes, too hot food, alcoholic beverages;
  • side effects of drugs;
  • permanent mechanical damage to the mucous membrane by the sharp edge of the tooth, unpolished seal, poor-quality of the orthopedic prosthesis;
  • galvanism of a seal, dentures, and other metal structures in the oral cavity.

Among the endogenous risk factors are the following violations in the work of the body:

  • diseases of the gastrointestinal tract;
  • hypovitaminosis (primarily a lack of vitamin A);
  • failures in metabolism (diabetes, hormone adjustment);
  • anemia;
  • chronic inflammatory processes in the oral cavity, mucous neuro dystrophic changes (in stomatitis, gingivitis, etc.);
  • presence in the body of HIV;
  • genetic predisposition to dyskeratosis.

Clinical manifestations – symptoms

symptoms leukoplakiaThe onset of the disease often is unnoticed, but since the mouth is more accessible for self-examination, the diagnosis of leukokeratosis usually occurs earlier than in the disease to other organs.

There are several forms of the disease, developing from one another. Flat leukokeratosis under unfavorable conditions becomes verrucous and further neglect of treatment leads to erosive form.

Separately, you can observe leukokeratosis in smokers. The possible presence of several forms simultaneously on different areas of the oral cavity, each of which can at any time to regenerate into a malignant neoplasm.

The first symptoms are usually observed in the field of chronic inflammation. The slightly blurred epithelium is replaced by translucent gray plaques that when iodine treatment remains a whitish color.

The diameter of the plaque does not exceed 1-2 inch. Outbreaks of the disease are formed:

  • on the mucous membrane of the cheeks, starting with the closing line of the teeth;
  • in the corners of the mouth and the edge of the lips;
  • on the sides of the tongue or on its back;
  • on the gums;
  • on the palate.

Their emergence takes from two weeks to several months. In the first stage horny areas seem noticeably swollen, but then only slightly raised above the surrounding tissues.

Palpation shows no condensation, but the damaged area of the mucous becomes rough to the touch and loses its shine.

Flat leukoplakia is generally painless. In some cases, there are complaints of dryness and tightness in the site of the lesion.

Coating hyperkeratosis spots, depending on the degree of keratinization changes from transparent gray to bright white. Sami spots have clearly defined edges and can be kept within these limits a lifetime without causing any discomfort.

However, the strengthening of external influences or violation of some functions of the body process of keratinization of the oral mucosa is accelerated, the density and size of plaques are increased. It speaks about a transition into a verrucous stage of the disease.


In this form of the disease severity of hyperkeratosis increases. Lesions are perceived as rough surface of sealing.

Their whitish color stands out against a background of healthy mucous membranes. Chapped areas are sensitive to the food temperature and respond with a pain to spicy or sour dishes.

  • Patchy form of verrucous leukokeratosis resembles corn protruding above the surrounding tissues, whose color varies from yellow to bluish-white.
  • Warty form becomes a hilly grayish growing, reaching a height of 0,1-0,2 inch.

The impetus to a rebirth of leukokeratosis into malignant tumor are ongoing irritation or other predisposing disorders in the body.

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This is a distinct disease which does not depend on a history of prior hyperkeratosis is a benign cancer of the oral mucosa. Nevertheless, it can be triggered by existing forms of leukokeratosis or develop under the influence of the same factors.

Effected mucosa looks swollen and pale (greyish), and the boundary growths are blurred. The hallmark is exfoliation of reborn cells, leading to the habit of biting towering areas.

Soft leukokeratosis is localized mainly along the line of the teeth closing on the inside of the cheek and lip edges.

Treatment at home and at the doctor’s

how to cure leukoplakiaSelf-diagnosis of leukokeratosis is not possible since the diagnosis requires confirmation by laboratory tests. There is a risk of the keratinized lesions getting worth therefore mandatory inspection point is a biopsy. It allows you to identify the cellular atypia characteristic of precancerous lesions.

If there is no immediate threat of regeneration into a malignant tumor, the fight against leukoplakia starts with conservative therapy. It is aimed at eliminating the factors that triggered the disease, and the normalization of metabolism in the epithelium.

It is recommended to give up smoking or reduction of consumed cigarettes. Spicy food and hot food are excluded from the diet. In the presence of abnormalities of the gastrointestinal tract, there’s a need for their treatment.

The problems of dental character are solved:

  • grind cutting projections, seal up damaged teeth;
  • change of attachment of dentures so that they do not injure the affected area;
  • dental implants should be polished; it is recommended that their production is of precious metals;
  • spend an additional therapy of infectious diseases of the oral cavity with taking leukokeratosis into account.

During treatment, pay special attention to oral hygiene:

  • disinfection solution with furatsillina, a weak solution of boric acid, a decoction of herbs.
  • teeth cleaning is performed with gentle movements without damaging keratinized plaques;
  • use mouthwashes and toothpaste with chlorophyll.

For local effects used applications of oily preparations: solutions tocopherol acetate, retinol, karotolin, tsigerol. It is important to avoid cautery plaque that leads only to increased keratinization and accelerates the transition to the erosive stage. The reception of vitamin A is prescribed, as well as immunomodulatory means and bracing means.

Most of these measures are performed at home or at the hospital. Usually, they are sufficient enough to eliminate the symptoms of a simple leukokeratosis or to bring it to a stable state.

Such procedures are as well appointed as the initial phase of treatment of verrucous and erosive forms. The absence of positive changes is the basis for surgical treatment.

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Folk remedies for the treatment

The traditional medicine has enough means to help to deal with the symptoms of cervical leukokeratosis, and other mucous membranes. These include vaginal douching, tampon insertion, and suppository with ointments based on vegetable oils and tinctures of eucalyptus, propolis, and calendula. Obviously, all this is not applied in the treatment when effecting affected mouth.

Therefore, the choice of the people’s choice will be aimed mainly at eliminating the factors that are conducive to the development of the disease:

  • To restore the functioning of the immune system herbal teas and decoctions are used: You can use any appropriate collection, to which there are no contraindications.
  • Freshly squeezed fruit and vegetables juices are not only to raise the immune system but are also a source of vitamin A. Especially a lot of it is contained in carrot, pumpkin, parsley, apricots. Made juice is diluted with water to protect the mucosa from extra stimuli. For the same reason avoid the use of citrus and other acidic fruit.
  • Local effects include oral care as a rinse decoction of chamomile, calendula, linden flowers, St. John’s wort and other herbs that have an antiseptic effect. During day hours, you can drink a strong green tea.
  • For local applications and with other pharmacy drugs the oil of sea buckthorn and wild rose is used.
  • Kalanchoe juice is used for patients with erosive and ulcerative lesions.

leukoplakia and its dangers

In a simple form of the disease, herbal drugs can have a supporting effect and sometimes even replace medication.

Nevertheless, we must not forget that the leukokeratosis is a precancerous condition, and the sooner the changed portions of the mucous will come back to normal, the less is the likeliness of an adverse outcome.

So do not neglect the more efficient modern techniques. It is advisable to complement traditional remedies only with treatments prescribed by the doctor.

After the disappearance of all symptoms of leukokeratosis in the mouth, it is necessary to continue to monitor the state of the mucous membranes. The disease tends to relapse, especially when resuming external irritants.

1 Comment Post comment

  • Ani

    13 Июль 2016 at 9:23


    For which diseases Zitcare Tablet is used? I am facing skin problem in mouth. What is the effect of Zitcare Tablet on Skin? My Disease name is Leucokeratosis in skin/mouth. Can I use Zitcare Tablet? Zitcare is used for Skin disease purpose?

    Also I want to know what is Leucokeratosis ?

    Thanks & regards,

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